With the total healthcare market set to hit $21 billion by 2025, India is becoming a high-leverage test bed for models that could extend far beyond national borders. For U.S. operators and VCs, it’s one of the few global markets showing both breadth and buyer urgency.
This list is a filtered look at where real traction is happening:
- Who’s closing large B2B deals
- Who’s threading clinical, digital, and distribution
- And who’s quietly setting up to enter or influence the U.S.
Some of these names are already scaling nationally. Others are just breaking out of pilot mode. All of them are worth watching — because the next phase of digital health won’t just be built in Silicon Valley.
21 Digital Health Startups Leading The Way
PharmEasy
Founded: 2015 | Location: Mumbai | Category: E‑Pharmacy
PharmEasy is one of India’s largest digital pharmacies, offering medicine delivery, diagnostics, and teleconsultation through a single platform.
The company has raised over $1 billion from Prosus, Bessemer, Temasek, TPG, B Capital, and MEMG (which led a $216M rights issue in 2024). After acquiring Medlife and a 66.1% stake in Thyrocare in 2021, PharmEasy expanded its diagnostics and offline network significantly. FY2024 revenue reached ₹5,664 Cr ($670M), with losses narrowing to ₹2,533 Cr ($300M). It had paused IPO plans in favor of recapitalizing for sustainable growth.
Tata 1mg
Founded: 2015 | Location: Gurgaon | Category: E‑Pharmacy & Diagnostics
Tata 1mg provides online pharmacy services, in-house lab testing, and virtual consults across 22+ specialties.
Now part of Tata Digital, the platform combines B2C scale with B2B partnerships and ABHA integration. By FY2023 it overtook PharmEasy as market leader, with 31% share vs. 15%. FY2024 revenue reached ₹1,968 Cr (~$230M). 1mg’s strength lies in its vertical integration, strong corporate backing, and deepening trust across consumer and clinical journeys.
Netmeds
Founded: 2015 | Location: Chennai | Category: E‑Pharmacy
Netmeds is an online pharmacy offering prescription and OTC drugs, wellness products, and home delivery to over 20,000 pin codes.
Acquired by Reliance Retail Ventures in 2020 (₹620 Cr / ~$72M), Netmeds now operates as part of Reliance’s larger healthcare retail strategy. Its platform has served 5.7M+ customers and lists 70,000+ medications. While no longer a venture-stage startup, its role as a scaled, corporate-backed distribution layer remains strategically important for India’s digital health infrastructure.
Orange Health Labs
Founded: 2020 | Location: Bangalore | Category: On-Demand Lab Diagnostics
Orange Health offers fast lab diagnostics with home sample collection and same-day digital reports.
Backed by General Catalyst, Bertelsmann India, Accel, and Amazon’s Smbhav Fund, it has raised over $47M. The company offers 2,000+ lab tests and has served more than 1M users in Bengaluru and National Capital Region (NCR). Orange Health is positioned as a logistics-first diagnostics layer with a clean consumer experience and hyperlocal expansion strategy.
mfine
Founded: 2017 | Location: Bangalore | Category: Telemedicine & AI Medicine
mfine is a virtual care platform offering teleconsultations, lab bookings, and e‑pharmacy, powered by AI-based triage.
The company has served over 3 million users and supports 300,000+ monthly transactions across services. It partners with 700+ diagnostic centers and 6,000 doctors, and has built a strong B2B channel with 500+ employer clients covering more than 500,000 employees. In 2021, mfine raised a $48M Series C co-led by BEENEXT and Moore Strategic Ventures. Its long-term play is a “virtual hospital” stack with end-to-end care delivery.
MediBuddy
Founded: 2013 | Location: Bangalore | Category: Telehealth Platform
MediBuddy is one of India’s largest digital healthcare platforms, combining 24×7 teleconsults, diagnostics, and e‑pharmacy services.
Following its 2020 merger with DocsApp, MediBuddy raised $125M in a Series C round led by Quadria Capital and Lightrock. As of 2024, the platform had reached 12.7 million users, supported by a provider network of tens of thousands of doctors. Its traction in both employer health and direct-to-consumer services positions it as a full-stack digital care provider.
Plum Telehealth
Founded: 2021 | Category: Telemedicine + Health Insurance
Plum Telehealth offers virtual consults bundled into B2B employee insurance products, with integrated scheduling, prescriptions, and reminders.
Its provider directory spans 20+ specialties, with features like gender and language filters, and WhatsApp/SMS reminders to support adherence. In May 2021, Plum raised $15.6M in Series A funding from Tiger Global, Surge, Tanglin Ventures, and several prominent angels. It’s positioned as a low-friction front door for India’s growing employer-sponsored health market.
Tattvan Eclinic
Founded: 2016 | Location: Gurugram | Category: Franchise Telemedicine
Tattvan converts rural clinics into telemedicine-enabled franchises, expanding access to specialist consults and diagnostics.
The company operates 600+ telemedicine hubs across 18+ states and 218+ districts. Its model offers a bridge between private healthcare systems and under-resourced rural geographies, leveraging both tech and trained onsite operators. With over nine years of operational learnings, Tattvan is quietly becoming a backbone player for Tier 3–4 telehealth access.
DigiQure E‑Clinic
Founded: 2020 | Location: Bhopal | Category: Local‑Clinic Telemedicine
DigiQure runs e‑clinics that provide video consults, digital prescriptions, and hospital referrals in semi-urban and rural areas.
It gained early attention after raising ₹40 lakh on Shark Tank India. The platform uses a franchise and partner-led growth model, making it capital-efficient and community-embedded. DigiQure reflects the growing demand for hyperlocal digital clinics in healthcare deserts.
CureBay
Founded: 2021 | Location: Bhubaneswar | Category: Hybrid Telemedicine
CureBay connects rural populations to quality care through e‑clinics staffed by trained health workers and powered by AI and logistics.
It operates 150+ clinics across Odisha and Chhattisgarh and serves 90,000 active members. After an early ₹50 Cr Series A from Elevar Equity, it raised a $21M Series B in 2024 from Bertelsmann India, British International Investment, and others. CureBay is one of the few rural-first care models showing both retention and expansion readiness.
DocVita
Founded: 2019 | Location: Pan‑India | Category: Mental Health
DocVita is a therapy platform offering online and offline access to licensed mental health professionals via WhatsApp and video consults.
The company enables asynchronous and scheduled care, with a focus on discreet access and user-centric onboarding. Backed by Y Combinator and Goodwater Capital, DocVita is building a consumer-first platform that meets patients where they already are — especially in a market where stigma and convenience remain critical barriers.
Lissun
Founded: 2021 | Location: Gurgaon | Category: Mental Health (Phygital)
Lissun provides hybrid mental health services across corporate, school, and hospital channels—integrating digital tools with in-person counseling.
The company raised $2.5M in a pre-Series A round led by RPSG Capital. Its strength lies in embedding care into existing institutions and providing longitudinal support across structured settings. Lissun is positioning itself as a plug-and-play mental health layer for institutions managing stress, anxiety, and early-stage intervention needs.
Mosaic Wellness
Founded: 2019 | Location: Mumbai | Category: Telehealth Coaching
Mosaic Wellness builds vertical digital health brands focused on niche life-stage and condition-specific needs such as men’s health, women’s wellness, and parenting.
Its D2C-first approach is supported by a clinical layer of digital consultations and coaching. The company has raised $68M from Peak XV, Elevation Capital, and Z47. With a playbook that combines personalized care and commerce, Mosaic is building a category portfolio model that mirrors U.S. platforms like Ro or Hims — tailored for Indian behavioral health and lifestyle segments.
Sugar.fit
Founded: 2021 | Location: Pan‑India | Category: Chronic Disease Management
Sugar.fit delivers diabetes care through a combination of wearable CGMs, real-time coaching, and personalized interventions.
The company has raised $16M to date, including a $5M round from B Capital. Its full-stack approach to diabetes management integrates lifestyle tracking, medication adherence, and diet support — all within a single consumer experience. Sugar.fit is part of the first wave of condition-specific platforms moving from engagement to outcomes.
Alyve Health
Founded: 2020 | Location: Mumbai | Category: Preventive Health Plans
Alyve Health offers subscription-based preventive care bundles that include doctor visits, lab tests, insurance, and pharmacy access.
It raised $5.5M in a Series A led by Axilor Ventures. Alyve’s model targets health-conscious urban users and insurers looking for bundled outpatient packages. By linking wellness with risk protection, the company is positioning itself as an ecosystem layer for both consumer and payer value chains.
Eka Care
Founded: 2020 | Location: Pan‑India | Category: EMR & Telemedicine
Eka Care is a digital health record platform designed to align with India’s Ayushman Bharat Health Account (ABHA) infrastructure, while also offering virtual consults and health tracking tools.
The platform enables users to store prescriptions, test results, and vaccine records, all linked to India’s national health ID. Eka Care raised a $15M Series A led by Hummingbird Ventures and is one of the few startups focused on health data continuity for consumers.
Ayu Health
Founded: 2019 | Location: Bengaluru | Category: Telemedicine + Surgery
Ayu Health partners with 150+ hospitals to manage claims processing using a centralized tech platform.
The company has processed 20k+ claims and served over 15K+ patients. With $39.7M raised from Stellaris, 57 Stars, and Capier, Ayu Health is standardizing hospital quality, pricing, and patient experience — essentially bringing network effects to fragmented care delivery.
MyHealthcare
Founded: 2017 | Location: Pan‑India | Category: Digital Care Integration
MyHealthcare connects patients, providers, labs, pharmacies, and caregivers into a unified digital ecosystem.
The company has raised $12.7M from Hunch Ventures. It supports multi-specialty hospitals and Outpatient Department OPD chains with tools for care navigation, patient monitoring, and integrated EMR systems. MyHealthcare is quietly becoming the connective tissue for mid-sized provider networks.
Heaps Health
Founded: 2020 | Location: Bengaluru | Category: Healthcare AI Analytics
HEAPS is a SaaS analytics platform that uses AI and machine learning to optimize clinical workflows, reduce cost, and improve care quality.
It raised $7.45M from NVS Wealth Managers and the Rajiv Dadlani group. HEAPS provides decision support and performance benchmarking tools to hospitals and insurers, giving operators clearer visibility into outcomes and spend. The product is data-heavy, back-end focused, and designed for enterprise integration.
HealthPlix
Founded: 2016 | Location: Bangalore | Category: EMR/SaaS
HealthPlix is an AI-enabled electronic medical record (EMR) platform built for Indian clinicians, offering personalized workflows, practice analytics, and clinical decision support.
Used by over 10,000 doctors across 370+ cities, the platform supports 30 million patient records and 80 million prescriptions. It has raised over $44M from Lightspeed, Chiratae Ventures, and JSW Ventures. HealthPlix is one of the few Indian SaaS players with strong doctor loyalty and signs of export potential into similar emerging markets.
Neuranics Lab
Founded: 2021 | Location: Delhi/Kharagpur | Category: Point-of-Care Diagnostics
Neuranics Lab is building a rapid CBC analyzer that delivers full blood count results in under 10 minutes from a finger-prick sample.
The company raised $700K in seed funding from Inflection Point Ventures. Designed for decentralized testing environments, Neuranics aims to replace slower lab workflows with compact, AI-powered diagnostics. Still early-stage, but with significant relevance for Tier 2/3 diagnostic scalability.
Signals for Investors: What These Startups Reveal
India’s digital health market is sending clearer signals in 2025, not just more companies, but models that may have a path to durability. While it’s too early to call winners, there are signs of where traction is starting to consolidate.
1. Infrastructure plays are getting a second look
Startups like HealthPlix, Eka Care, and HEAPS suggest that the market may be more ready for tools that enable care delivery, not just patient acquisition. ABHA integration and hospital demand for reporting and analytics could give these players more staying power than earlier EMR entrants.
2. Rural-first models may not stay niche
CureBay, Tattvan, and DigiQure show that hybrid delivery — digital triage plus localized support — can move beyond pilot mode in underserved geographies. If current momentum holds, these companies could be early examples of how care access expands without relying entirely on public infrastructure.
3. Consumer platforms are bending toward clinical outcomes
Sugar.fit, Mosaic Wellness, and Plum Telehealth are blending consumer-grade UX with workflows that resemble clinical care. While not all may be reimbursable yet, some are starting to align with payers, employers, or wellness programs — hinting at a shift from lifestyle to longitudinal models.
What this could mean for investors:
- D2C-only plays may still work for specific niches, but several of the most active companies are building in ways that create optionality: B2B2C channels, employer logic, or embedded infrastructure.
- A few of these models share contours with U.S. or EU equivalents, but with faster iteration cycles and lower implementation costs.
- Startups here are often solving operational and engagement challenges that are relevant well beyond India — even if the go-to-market playbooks look different.
For investors exploring cross-border strategies, these startups may offer not just growth exposure, but insight into where cost-sensitive care delivery is headed.
Final Thoughts on Digital Health Startups in India
India’s digital health market in 2025 isn’t a blank-slate opportunity. It’s a layered, fast-moving ecosystem where early bets are starting to clarify. Platform consolidation is underway. Infrastructure players are maturing. And a handful of regional leaders are beginning to position beyond domestic scale.
For U.S. founders and operators, this market may offer more than growth — it may offer strategic leverage. That could mean distribution partnerships, co-development models, or insights from teams solving for care delivery under real cost and access constraints.
And for Indian startups eyeing the U.S., many of the fundamentals — chronic care logic, SaaS enablement, hybrid delivery — are already aligned. What often needs translation is go-to-market execution, pricing, and US buyer narrative.
If you’re scaling out of India and looking to sharpen your U.S. market entry — we can help.
At Accretive Edge, we work with digital health leaders to connect strategy to revenue:
- Refining positioning for global buyers
- Mapping market-entry and GTM pathways
- Preparing for cross-border capital or partnerships
